XMD-17-51 Trifluoroacetate ( XMD-17-51 Trifluoroacetate (1628614-50-5 free base) )

Catalog No. M24121 CAS No. 2436579-93-8

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Product Name

XMD-17-51 Trifluoroacetate
Note

Research use only, not for human use.
Brief Description

XMD-17-51 Trifluoroacetate is a potent and highly selective NUAK1 inhibitor.
Description

XMD-17-51 Trifluoroacetate is a potent and highly selective NUAK1 inhibitor.
In Vitro

XMD-17-51 TFA is a pyrimido-diazepinone compound that is able to modulate protein kinases, including MPS1 (TTK), ERK5 (BMK1, MAPK7), polo kinase 1, 2, 3, or 4, Ack1, Ack2, Abl, DCAMKL1, ABL1, Abl mutants, DCAMKL2, ARK5, BRK, MKNK2, FGFR4, TNK1, PLK, ULK2, PLK, PRKD1, PRKD2, PRKD3, ROS1, RPS6KA6, TAOK1, TAOK3, TNK2, Bcr-Abl, GAK, cSrc, TPR-Met, Tie2, MET, FGFR3, Aurora, Axl, Bmx, BTK, c-kit, CHK2, Flt3, MST2, p70S6K, PDGFR, PKB, PKC, Raf, ROCK-H, Rsk1, SGK, TrkA, TrkB and TrkC, and can be used in the treatment of various diseases, disorders or conditions.
In Vivo

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Synonyms

XMD-17-51 Trifluoroacetate (1628614-50-5 free base)
Pathway

Membrane Transporter/Ion Channel
Target

AMPK
Recptor

NUAK1
Research Area

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Indication

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CAS Number

2436579-93-8
Formula Weight

518.49
Molecular Formula

C23H25F3N8O3
Purity

>98% (HPLC)
Solubility

DMSO:80 mg/ml (197.78 mM); Ethanol:8 mg/ml (19.78 mM); Water:2 mg/ml (4.94 mM)
SMILES

O=C1N(C)C2=CN=C(NC3=CN(C4CCNCC4)N=C3)N=C2N(C)C5=CC=CC=C15.FC(C(O)=O)(F)F
Chemical Name

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